Research | Research publications

Technical Journals

Ayodeji, O.; Graham, E.; Kniss, D.; Lannutti, J.; Tomasko, D., Carbon Dioxide Impregnation of Electrospun Polycaprolactone Fibers. The Journal of Supercritical Fluids 2007, in press.
Yunling Bai, Wei-Cho Huang, and S.T. Yang, Enzyme-Linked Immunosorbent Assay of Escherichia coli O157:H7 in Surface Enhanced Poly(methyl methacrylate) Microchannels, Biotechnol. Bioeng., in press (2007).
Y. Bai, M. Boreman, C.G. Koh, Y.-J. Juang, I.C. Tang, L.J. Lee, and S.T. Yang, Surface Modification for Enhancing Antibody Binding on Polymer-Based Microfluidic Device for Enzyme-Linked Immunosorbent Assay, Langmuir, 22(22) 9458-9467 (2006).
Y. Chen, L. Li, A. Y. Yi, „Fabrication of precision 3D micro structures by use of a combination of ultraprecision diamond turning and reactive ion etching process,‰ in press, Journal of Micromechanics and Microengineering, March (2007).
N.-R. Chiou, L. J. Lee, and A.J. Epstein, Synthesis of Porous Membrane Controlled Polymerization, of Nanofibers of Polyaniline and Its Derivatives, submitted to Advance Materials.
N-R. Chiou, C. Lu, J. Guan, L. J. Lee, and A.J. Epstein, Synthesis and Applications of Aligned Polyaniline and Polypyrrole Nanofibers, submitted to Polymer Preprints.
N-R Chiou, C. Lu, L.J. Lee and A.J. Epstein, Aligned Polyaniline Nanofibers, Nature Nanotechnology, accepted.
H.W. Choi, D.F. Farson, C.M. Lu, L.J. Lee: „Femtosecond bulk laser micromachining of microfluid channels in PMMA‰, Journal of Laser Applications, 18, 210-215, (Aug. 2006).
Choi, H. W.; Johnson, J. K.; Nam, J.; Farson, D. F.; Lannutti, J. J., Structuring electrospun polycaprolactone nanofiber tissue scaffolds by femtosecond laser ablation. J. Laser Applications 2007, 19, (4).
Deschner, J.; Perera, P.; Wang, Z.; Lannutti, J.; Agarwal, S., Regenerative potential of biomechanical signals in cartilage repair: A molecular analysis in vitro. Tissue Engineering 2006, 12, (4), 998-998.
Lunhan Ding and Susan V. Olesik, Controlled Synthesis of Carbon Nanoparticles with Narrow Size Distribution via poly(4-ethynyl styrene), submitted and accepted by Carbon.
Duling, R. R.; Dupaix, R. B.; Katsube, N.; Lannutti, J., Mechanical characterization of electrospun polycaprolactone (PCL): a potential scaffold for tissue engineering. Journal of Biomechanical Engineering 2007, accepted.
J. Guan, B. Yu and L.J. Lee, Formation of DNA and Polymeric Nanowires on Micropillars by Dewetting, Advanced Materials, in press.
J. Guan, N. Ferrell, L.J. Lee and D.J. Hansford, "Fabrication of Polymeric Microparticles for Drug Delivery by Soft Lithography," Biomaterials, _27_, 4034-4041 (2006).
J. Guan, H. He, L.J. Lee and D.J. Hansford, Fabrication of Particulate Reservoir-Containing, Capsule-Like, and Self-Foldable Polymer Microstructures for Drug Delivery, Small, accepted.
Ali A. Hassanali and Sherwin J. Singer, ``Static and dynamic properties of the water/amorphous silica interface: a model for the undissociated surface'', J.Computer-Aided Materials Design, 14(1):53 (2007).
Ali Hassanali and Sherwin J. Singer, ``A model for the water/amorphous silica interface: the undissociated surface'', J. Phys. Chem.(submitted, 2006 - accepted pending revisions)
H. He, L. Li and L. J. Lee, Photopolymerization and Structure Formation of Methacrylic Acid Based Hydrogels in Water/Ethanol Mixture, Polymer, _47_, 1612-1619 (2006).
H. He, J. Guan, L.J. Lee and D.J. Hansford, "An Oral Delivery Device Based on Self-Folding Hydrogels", Journal of Controlled Release, _110_, 339-346 (2006).
X. Hu, S. Wang, Y-J Juang and L.J. Lee, Five-cross Microfluidic Network Design Free of Coupling between Electrophoretic Motion and Electro-osmotic Flow, Applied Physical Letters, _89_, 084101 (2006) {selected for the September 4, 2006 issue of Virtual Journal of Nanoscale Science & Technology}.
Johnson, J.; Ghosh, A.; Lannutti, J., Microstructure-Property Relationships in a Tissue Engineering Scaffold. Journal Of Applied Polymer Science 2007, in press.
H. C. Jung, W. Lu, Shengnian Wang, L. J. Lee, and X. Hu, "Etching of Pyrex Glass Substrates by ICP-RIE for Micro/Nanofluidic Devices", Journal of Vacuum Science & Technology B: Microelectronics and Nanometer Structures, 24(6), 3162-3164 (2006).
K. Kang, L.J. Lee and K.W. Koelling, Microdevice End Pressure Evaluations with Bagley Correction", Microfluidics and Nanofluidics, _2(3)_, 223-235 (2006).
Kang X, Xie Y, Powell H, Lee J, Belury M, Lannutti JJ, and Kniss DA. Adipogenesis of murine embryonic stem cells in a three-dimensional culture system using electrospun polymer scaffolds, Biomaterials 2007; 28(3): 450-8.
Kristen E La Flamme, Ketul C Popat, Lara Leoni, Erica Markiewicz, Thomas J La Tempa, Craig A Grimes, Tejal A Desai. Biocompatibility of nanoporous alumina membranes for immunoisolation, Biomaterials, in press Jan 2007.
Lannutti, J.; Reneker, D.; Ma, T.; Tomasko, D.; Farson, D., Electrospinning for tissue engineering scaffolds. Materials Science and Engineering: C 2007, 27, 504ˆ509.
L.J. Lee, Polymer Nanoengineering for Biomedical Applications", Annals of Biomedical Engineering, _(34)1_, 75-88 (2006).
L.J. Lee, Nanoscale Polymer Fabrication for Biomedical Applications, in Volume Biomedical and Biological Nanotechnology in the Kluwer Series of _BioMEMS and Biomedical Nanotechnology_, Edited by M. Ferrari, Springer Science, Ch. 3, pp 51-96, 2006.
L.J. Lee, L. Yu, K.W. Koelling, and M.J. Madou, Injection Molding for Microfluidic Applications in _Precision Injection Molding_, Edited by J. Greener and R.Wimberger-Friedl, Hanser/Gardner Publications, Ch. 8, pp 169-238, 2006.
L. J. Lee, S-T Yang, S. Lai, Y. Bai, W-C Huang and Y-J Juang, Microfluidic Enzyme-Linked Immunosorbent Assay (ELISA) Technology in _Advances in Clinical Chemistry, Volume 42_, Edited by G. Makowski, Elsevier Inc., pp 255-295, 2006.
Lei Li, Allen Y. Yi, David A. Grewell, Avraham Benatar and Yang Chen, "Fabrication of Diffractive Optics by use of Slow Tool Servo Diamond Turning Process," Optical Engineering, 45(11) 113401 (Nov. 2006).
Liu, D., Tomasko, D.L., CO2-Induced Sorption and Dilation of Poly(glycolide-co-lactide) copolymers, J. Supercrit. Fluids, 2007, 39(3), 416-425.
Carlos Lopez, Aaron Fleischman, Shuvo Roy, and T.A. Desai, "Characterization of PC12 Cells in Silicon Based Microenvironments" Biomaterials, 2006 Jun;27(16):3075-83.
C. Lu, Y. Xie, M-C Cheng, Y. Yang, C-G Koh, L.J. Lee and Y-J Juang, New Valving and Bonding Methods for Microfluidic Biochips Containing Proteins, Analytical Chemistry, published on web 12/20/2006.
C. Lu, M-C Cheng and L.J. Lee, Sacrificial Template based Micro-Embossing, Polymer Engineering & Science, in press.
Chunmeng Lu, Mark Ming-Cheng Cheng, Avraham Benatar and L. James Lee, "Embossing of High-Aspect-Ratio-Microstructures (HARMS) Using Sacrificial Templates and Fast Surface Heating," to appear in Polymer Engineering and Science.
Nam, J.; Huang, Y.; Agarwal, S.; Lannutti, J., Enhanced chondrocytic cell response to an electrospun topography. Langmuir 2007, submitted.
Nam, J.; Huang, Y.; Agarwal, S.; Lannutti, J., Improved Cellular Infiltration in Electrospun Fiber via Engineered Porosity. Tissue Engineering 2007, accepted.
Robin Ng, Nan-Rong Chiou, Arthur J. Epstein, Shang-Tian Yang, Astrocytes Interactions with Polyaniline Nanofibers, Biomaterials, in review (2007).
Pan, X., Wu, G., Yang, W., Barth, R.F., Tjarks, W., and Lee, R.J. Synthesis of Cetuximab-Immunoliposomes via a Cholesterol-Based Membrane Anchor for Targeting of EGFR. Bioconjug. Chem. (2007) 18:101-108.
Pan, X. and Lee, R.J. Construction of anti-EGFR immunoliposomes via folatefolate binding protein affinity. Int. J. Pharm., (2007), in press.
X. Pan, J. Guan, L.J. Lee and R.J. Lee, Cationic Lipid Coated Magnetic Nanoparticles Associated with Transferrin for Gene Delivery, Journal of Controlled Release, accepted.
Kidong Park, Demir Akin, Rashid Bashir, Electrical Capture and Lysing of Viruses in Silicon Nanoprobe Array, Submitted, 2007.
Powell, H. M.; Kniss, D. A.; Lannutti, J. J., Nanotopographic control of cytoskeletal organization. Langmuir 2006, 22, (11), 5087-5094.
Mayur Savla, Sharon Schreiber, Daniel F. Iscru, Camelia Selcu, Dennis Pokholov, P. Chris Hammel, Roger Proksch and Gunjan Agarwal, Magnetic Force Microscopy of Super-Paramagnetic Nanoparticles, (submitted).
Michael L. Schuette and Wu Lu, „Compositional study of copper-germanium ohmic contact to n-GaN‰, Journal of Electronic Materials, vol. 36, pp. xx-xx, 2007.
Junghui Song, Jeffrey S. Flynn, George R. Brandes, and Wu Lu, „Polarity detectable chemical sensors based on AlGaN/GaN heterostructures field effect transistors,‰ Applied Physics Letters, vol. 89/22, pp. 223503-1 ˆ 223503-3, 2006.
A. Srivastava, S. Ghosh, Y. Yang, and L.J. Lee. An computational-experimental study of glass transition temperature variation in thin films (to be submitted, Macromolecule).
Timothy B. Stachowiak, Dieudonne A. Mair, Tyler G. Holden , L. James Lee, Frantisek Svec, Jean M. J. Frechet: Hydrophilic surface modification of cyclic olefin copolymer microfluidic chips using sequential photografting. Journal of Separation Science, 30, 2007, accepted.
Anka N. Veleva, Stuart L. Cooper, Cam Patterson. Selection and Initial Characterization of Novel Peptide Ligands that Bind Specifically to Human Blood Outgrowth Endothelial Cells. Biotechnology and Bioengineering. (Submitted)
S. Wang and L.J. Lee, Electrokinetically Assisted Dynamic Assembly in Microfluidics, Journal of American Chemistry Society, 127(2), 254-255 (2007).
Nobuhiko Watari, Makino Masato, Norio Kikuchi, Ronald G. Larson and Masao Doi, „Simulation of DNA motion in a microchannel using stochastic rotation dynamics‰, online in Journal of Chemical Physics 126, 094902 (2007).
Y. Yang, M-C Cheng, X. Hu, L.J. Lee, R. Goyette, and M. Ferrari, CO_2 Enhanced Polymer Surface Dynamics below the Bulk Glass Transition Temperature, Macromolecules, in press.
S.T. Yang and Robin Ng, 3D Cultures for Growing and Studying Cells, Materials Today, 10(3):56 (2007).
Y. Yang, D. Liu, L.J. Lee, and D.L. Tomasko, Low Temperature Fusion of Polymeric Nanostructures Using Carbon Dioxide, Advanced Materials, _19(2)_, 251-254 (2007).
Y. Yang, Y. Xie, X. Kang, L.J. Lee and D.A. Kniss, Assembly of 3D Cell-Scaffold Constructs Using Carbon Dioxide, Journal of American Chemistry Society, published on web 10/26/2006.
Y. Yang, A. Srivastava, S. Ghosh, and L.J. Lee. Molecular Dynamics validation of Substrate Effect on the Glass Transition Temperature of Polystyrene based nano-composite. (to be submitted, Journal of Physical Chemistry, B)
Yang Y, Liu D, Xie Y, Lee LJ, Tomasko DL. Low-Temperature Fusion of Polymeric Nanostructures Using Carbon Dioxide. Adv Mater. 2007, 19(2), 251-254.
A. Y. Yi, Y. Chen, F. Klocke, G. Pongs, A. Demmer, D. Grewell, and A. Benatar, A high volume precision compression molding process of glass diffractive optics by use of a micromachined fused silica wafer mold and low Tg optical glass, Journal of Micromechanics and Microengineering, Vol. 16, pp. 2000-5, 2006.
J. Zou and W. S. W. Ho, „CO2-Selective Polymeric Membranes Containing Amines in Crosslinked Poly(vinyl alcohol)‰, J. Membr. Sci., 286, 310-321 (2006).
Xie Y, Yang Y, Kang X, Lee LJ, and Kniss DA. Bioassembly of three-dimensional embryonic stem cell-scaffold complexes using compressed nitrogen or carbon dioxide, To be submitted to Stem Cells.

Conference Proceedings

Allam, Y., Tomasko, D.L., Merrill, J., Trott, B., Schlosser, P., Clingan, P. - Lab-on-a-chip Design-Build Project with a Nanotechnology Component in a Freshman Engineering Course, Proceedings of ASEE Annual Conference, Chicago, IL (2006), paper 2326. (peer reviewed)
Chen H, Ho M, Wang J, Leong KW. „Quantitative Model of Intracellular Trafficking Constructed from Quantum Dot-FRET,‰ Annual Meeting, Biomedical Engineering Society, Chicago, October, 2006.
Chen H, Ho M, Wang J, Leong KW. „Intracellular Trafficking of QD-Fret Nanoparticles for Gene Delivery,‰ Annual Meeting, American Society of Gene Therapy, Baltimore, May, 2006.
H.W. Choi, B. Zimmerman, D.F. F Farson, J.J. Chalmers: „Characterization of glass machining by femtosecond laser‰, Proceedings IMID 2006, Daegu Korea, Aug. 2006.
H.W. Choi, J. Johnson, D.F. Farson, J.J. Lannutti: „Femtosecond Laser Structuring of PCL and PET Electrospun Nanofiber Mesh‰, Proceedings ICALEO06, Scottsdale, AZ. LIA, Oct. 2006.
H.W. Choi, B. Zimmerman, J. Steach, D.F. Farson, J.J. Chalmers, D.V. Olesik: „Femtosecond Laser Machining of Dielectric Materials for Biomedical Applications‰, Proceedings ICALEO06, Scottsdale, AZ. LIA, Oct., 2006.
Clingan, P., Tomasko, D.L., Merrill, J., Allam, Y. - Work in Progress: Micro-/Nano-Technology Lab-on-a-chip Research Project for First-Year Honors Engineering Program 36th Annual Frontiers in Education Conference, San Diego, CA (2006), (peer reviewed)
Lei Chen and A. T. Conlisk, ``Electroosmotic Flow in Micro- and Nanonozzles, AIAA paper 2007-0931, 45th Aerospace Sciences Meeting, Reno, NV, January 8-11, 2007.
L. Chen and A. T. Conlisk, Mathematical Modeling of Electro-osmotic Flow in Micro-/Nano-nozzles, American Physical Society 58th Annual Meeting of the Division of Fluid Dynamics, 2006.
O Hemminger, Z Yu, C. Zhang, J. Lee and LS Fan, Microfluidic velocity measurements using three-dimensional confocal micro particle tracking velocimetry (CM-PTV), "Fluidization-XII" edited by Berruti, F., X. Bi., and T. Pugdley, Engineering Conference Institute (in press, 2006).
Hyun Chul Jung, Shengnian Wang, L. James Lee, and Wu Lu, „Etching of pyrex glass substrates by ICP-RIE for micro/nanofluidic devices‰, The 50th International Conference on Electron, Ion and Photon Beam Technology and Nanofabrication, Baltimore, MD, 2006.
Miranda Marcus and Avraham Benatar, "Experiments with Combined Ultrasonic and Laser Embossing of Microchannels in PMMA", accepted for Proceedings of Society of Plastics Engineering Annual Technical Conference, May 2007.
Kidong Park, Demir Akin, and Rashid Bashir, "A Microfluidic Chip With A Nanoscale Array For Analysis Of Virus Particles", Tenth International Conference on Miniaturized Systems for Chemistry and Life Sciences (TAS), Tokyo International Forum, Tokyo, Japan November 5th - 9th, 2006.
Darrell H Reneker, Tao Han, Electrical Bending and Mechanical Buckling Instabilities in Electrospinning Jets, Proceedings of the Materials Research Society, Boston, November 2006.
Mike Schuette and Wu Lu, „Investigation of low-temperature Cu3Ge ohmic contact to n-GaN‰, The 48th Electronic Material Conference, University Park, PA, 2006.
M. Talreja, I. Kusaka, and D. L. Tomasko, "Density functional approach for modeling polymer CO$_2$ interfaces," Midwest Thermodynamics and Statistical Mechanics, Akron, Ohio.
Manish Talreja, Isamu Kusaka, and David Tomasko, „Density functional approach for modeling polymer-CO$_2$ interfaces,‰ AIChE Annual Meeting, San Francisco, California.
Y. Xie, Y. Yang, X. Kang, L. J. Lee, D. A. Kniss. Assembly of embryonic stem cell/scaffold three-dimensional constructs using carbon dioxide assisted polymer fusion. The 2006 Annual Meeting of AIChE, 567a, 2006.
Yang Y, Xie Y, Kang X, Lee LJ, and Kniss DA. Assembly of three-dimensional polymeric constructs containing cells/biomolecules using carbon dioxide, Journal of the American Chemical Society 2006; 128(43):14040-1.
Y. Yang, Y. Xie, X. Kang, L. J. Lee, D. A. Kniss. Three-dimensional Assembly of biomedical micro/nanodevices containing cells/biomolecules using carbon dioxide. The 2006 Annual Meeting of AIChE, 579e, 2006.
Y. Yang, Y. Xie, L. J. Lee, D. A. Kniss. A generalized approach to construction of complex tissues. The 2005 Annual Meeting of AIChE, 142ax, 2005.
Zhu, D., Lennon, S.P., Peters, M.H., Finney, W.C., and Singh, M., Brownian Diffusion and Surface Kinetics of Liposome and Viral Particle Uptake by Human Lung Cancer Cells In-Vitro, Annals of Biomedical Engineering, 34,1573-1586, (2006).
L.B. Zimmerman, W.W. Choi, J.J. Chalmers, L.J. Lee, D.F. Farson: „Magnetic Particle Sorting in Microfluidic Devices Fabricated Via Femtosecond Laser Ablation with Surface Modification‰. Proceedings AIChe Annual Meeting, San Francisco, CA. AIChE, Nov. 2006.