CoreTechs
Affordable Nanomanufacturing
- Femtosecond Laser Processing for Biomedical Device Fabrication (Farson)
- Research on Non-Cleanroom Micromachining and High Precision Surface Finish (Yi)
- Microfabrication of Membrane Sandwich Electroporation Devices for Drug/Gene Delivery (Lu)
- Pt/AlGaN/GaN Heterojunction Field Effect Transistor Hydrogen Sensors at High Temperatures (Lu)
- Fabrication of Microfluidic Channel Devices in SU-8 (Lu)
- AlGaN/GaN Field Effect Transistors for Protein Detection in Physiological Buffer (Lu)
- AlGaN/GaN FET Sensor for Label Free Detection of DNA Hybridization (Lu)
Self and Dynamic Assembly
- Immobilization of Enzymes onto Porous Monolithic Polymer Supports to Facilitate Fabrication of Micro- and Nanofactories (Frechet)
- Fabrication of DNA Nanowire Arrays and Nanochannel Array for DNA Manipulation (L.J. Lee)
- Synthesis and Characterization of Nanoporous PCL Membranes for Controlled Drug Release (Ho)
- Development of Separation Devices/Media for Biomolecule Separations (Olesik)
- Peptide-Templated Deposition of Gold and CaMoO4 Nanoparticles for Biosensor Applications (Hansford)
Micro-/Nanofluidics
- Brownian Dynamics Simulation of DNA Conformational Trapping in a Micro-Mixing Flow (Larson)
- Single DNA Dynamics in Micropillar Array (L.J. Lee)
- Modeling of Electro-osmotic Flow and Particle Transport in Micro-/Nanonozzles (Conlisk)
- Molecular Simulations in Nanochannels: Modeling the Nanofactory (Singer)
- Multiscale Transport in Microfluidic and Nanofluidic Systems (Chella)
- Experiment and Numerical Simulation of Gas-Liquid Flow in Microchannels (Fan)
- High-Speed Confocal Micoscopy (Fan, L.J. Lee)
- Instantaneous DNA Electrophoretic Mobility (L.J. Lee)
- Issues in the Practical Design of a Biomolecule Separation Device Using Two-Phase Coating Flow (Koelling)
Nanomanipulation
- Living Cantilever Array: Characterization of Living Cells Through Mass Measurements (Bashir)
- Massively Parallel Positioning of Dip-Pen Lithography Arrays (Culpepper)
- Nanoscale Manipulation and Characterization Using Optical Tweezers (Lafyatis)
- Nanomanipulation Core Technology (Agarwal)
Nanofiber Synthesis
- Electrospinning for Multi-Cellular, Multifunctional Polymeric Devices for Biomedicine (Lannutti)
- Bioactive Electrospun Polymer Scaffold Tuned to the Selective Adhesion of Human Blood Outgrowth Endothelial Cells for Cardiovascular Applications (Cooper)
- Coiled Fibers for Medical Applications (Reneker)
Super-/Subcritical Fluids
- Novel Dense CO2 Technique for β-galactosidase Immobilization in Polystyrene Microchannels (Tomasko)
- Polymer Thin Film Modeling with Silica Substrate in Presence of Carbon Dioxide (Ghosh)
- Density Functional Approach for Modeling Polymer-CO2 Interfaces (Kusaka)
- Free-Volume, Surface and Interfacial Analysis in Polymers, Thin Films and Nanocomposites Using Positron Annihilation Spectroscopy (Jean)
Testbeds
Biosensors/-chips
- Cellular and Molecular Magnetic Separation (Chalmers)
- Water Molecular Distribution and Hydration Studies of a Voltage Gated Potassium Channel or Nanopore (Peters)
- Micro- and Nanoscale Devices for DNA Dynamics and Separations (L.J. Lee)
Nanofluidic Drug/Gene Delivery
- Targeted Delivery of Anti-Sense Oligonucleotides for Leukemia Therapy Using Immunolipopolyplex (ILP) (Bob Lee, Byrd, L.J. Lee, Marcucci)
- Nanoparticles Synthesized by Microfluidic Hydrodynamic Focusing (MHF) Devices for Gene Delivery Into Embryonic Stem Cells and Leukemia Cells (L.J. Lee)
- Liposomal Encapsulation of Flavopiridol for the Treatment of Chronic Lymphocytic Leukemia (Bob Lee)
- miRNA Delivery to Leukemia Cells Through TfR-Targeted Liposomes (Bob Lee)
- Nanoparticles for Drug and Gene Delivery via Electrohydrodynamic Spraying (Wyslouzil)
- Cell Patch and Membrane Sandwich Electroporation (L.J. Lee)
- Continuous Flow Electroporation (L.J. Lee)
- Elucidating the Fate of Polymer-DNA Nanoparticles in Oral Gene Delivery (Leong)
Cell-Based Devices and Constructs
- Cardiac Regeneration Through Temporal Release of Growth Factors from 3D Micro-Rod Scaffolds (Desai)
- Culturing Mammary Epithelial Cells in Three Dimensions (Kniss)
- 3D Tissue Culture in a Microfluidic Bioreactor Array (Yang)
- Stem Cellular Assembly of Vascular Tissue (Peters)